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101.

TEDTalks [electronic resource]: Juan Enriquez, Decoding the Future With Genomics

Scientific discoveries, futurist Juan Enriquez notes, demand a shift in code, and our ability to thrive depends on our mastery of that code. In this TEDTalk, he applies that concept to the field of genomics. A broad thinker who studies the intersection of science, business, and society, Enriquez has a talent for bridging disciplines to build a coherent look ahead. Says Nicholas Negroponte: "Juan Enriquez will change your view of change itself."
Online
2007
102.

TEDTalks [electronic resource]: Paul Rothemund, Casting Spells With DNA

Paul Rothemund won a MacArthur fellowship to pursue research in a fairly esoteric area of study: the folding of DNA. Rothemund's work combines the study of self-assembly with DNA nanotechnology and points the way toward self-assembling devices at microscale, making computer memory, for instance, smaller, faster, and maybe even cheaper. In this TEDTalk, Rothemund provides an overview of DNA origami.
Online
2007
103.

TEDTalks [electronic resource]: Spencer Wells, Building a Family Tree for All Humanity

Geneticist Spencer Wells studies not just human evolution but human diversity. Known for, among other achievements, his groundbreaking recognition of Central Asia as a major factor in the global diaspora of Homo sapiens, Wells has contributed greatly to the study of genetic variation and the single, common source from which our astonishing diversity emerged. In this TEDTalk, he describes how the Genographic Project is charting new areas of knowledge about the migratory history of the human species.
Online
2008
104.

TEDTalks [electronic resource]: Paul Rothemund, the Astonishing Promise of DNA Folding

Paul Rothemund folds DNA into shapes and patterns that look almost decorative to the average viewer. But his process is much more than microscopic origami - it carries vast implications for science and technology, and may one day allow scientists to create tiny self-assembling machines. In this TEDTalk, Rothemund lays out in clear, abundant detail the immense promise of DNA folding for computing, manufacturing, and other fields.
Online
2008
105.

TEDTalks [electronic resource]: Svante Paabo, DNA Clues to Our Inner Neanderthal

In this TEDTalk, geneticist Svante Paabo offers biological proof that early humans mated with Neanderthals after migrating out of Africa. Paabo also provides an overview of mutations and genetic variance, giving audiences a clear picture of the types of early hominids that lived in Africa, Europe, and the Middle East 100,000 years ago. Paabo explores human genetic evolution by analyzing DNA extracted from ancient sources, and worked with the team that presented the first version of the Neanderthal genome.
Online
2011
106.

TEDTalks [electronic resource]: Lee Cronin, Making Matter Come Alive

How improbable is it that life arose on Earth from inorganic matter? Could the process have involved a type of chemistry different from that which is known today? Using an expansive definition of life, chemist Lee Cronin is exploring these questions by attempting to create a fully inorganic cell using molecules that can assemble, replicate, and compete. In this provocative TEDTalk Cronin shares his research, touching on Darwinian evolution, inorganic biology, and new ways to define "life."
Online
2011
107.

TEDTalks [electronic resource]: Daniel Wolpert, the Real Reason for Brains

Neuroscientist Daniel Wolpert starts from a surprising premise: the brain evolved not to think or feel, but to control movement. Wolpert emphasizes the importance of movement by pointing out that all communication - speech, gestures, writing, sign language - is mediated through muscular contraction. In this entertaining, informative TEDTalk, Wolpert provides a glimpse into human motion and how and why the brain creates it.
Online
2011
108.

TEDTalks [electronic resource]: Cynthia Kenyon, Experiments That Hint of Longer Lives

Researchers have found a genetic mutation that doubles the lifespan of roundworms; what may be even more important is that the elderly worms have as much vigor and reproductive potency as when they were younger, and are more resistant to age-related disease than are normally-aging worms. In this TEDTalk biochemist Cynthia Kenyon explains how the daf-2 mutation works to increase longevity in insects and mice, and its implications for human beings.
Online
2011
109.

Fossils [electronic resource]: Reptiles and Mammals

This program presents fossil evidence for the evolution of reptiles and amphibians; explains the reasoning processes scientists must use when no direct evidence is available for examination; illustrates field techniques for collecting fragile fossils for transportation to the laboratory, where examination can take place under controlled conditions; and traces the evolution of some modern mammals back through time. After viewing the program, students should know which major features distinguish amphibians from reptiles, when and for how long reptiles were the dominant land animals and by whom they were replaced, and recognize the feature in the fossil remains of land reptiles that may indicate that they gave rise to mammals.
Online
2005; 1988
110.

Origins of Change [electronic resource]: Heredity and Mutation

This program introduces the concepts of naturally occurring and artificially induced mutagens, demonstrates how X-radiation and chemical additives can produce genetic mutations, introduces Dr. Maclyn McCarty (one of three researchers who identified DNA as the substance that transformed one variety of Pneumococcus into another), and shows how DNA is extracted and precipitated. After viewing the program, students should understand why Drosophila melanogaster is so well-suited to genetic investigation, how mutation can be induced by chemicals, and how inherited variation is the result of a change in the genetic code of DNA.
Online
2005; 1988
111.

DNA and the Evidence for Evolution [electronic resource]

This program shows the structure and replicating processes of DNA and the effect of genetic mutation; demonstrates the Lederberg Experiment; and recapitulates the evidence provided by fossils and structural and biological homologies that the process of adaptation and the selection of adaptors rests on a wide range of genetic variability. After viewing the program, students should have a general understanding of the general structure and functioning of DNA and of the Lederberg Experiment and its significance, and should be familiar with the range and types of evidence for evolution presented in the review section.
Online
2005; 1988
112.

Genetic Testing [electronic resource]

This program from The Doctor Is In demonstrates amniocentesis and ultrasound; outlines the advantages of knowing in advance that certain medical procedures are required to save a newborn, and the burden on parents of having to decide whether to terminate a pregnancy; and shows the advantages of avoiding cigarettes and alcohol during pregnancy.
Online
2009; 1990
113.

Darwin's Theory Today [electronic resource]

Since Darwin's day, explanations for the causation of evolution have come and gone, Lamarckism, mutationism, and the existence of a built-in mechanism driving to perfection all dismissed for lack of evidence and the proofs of molecular biology. Ernst Mayr examines and evaluates the modifications and adaptations to Darwin's theory of natural selection, to determine whether the resulting synthesis is indeed still Darwin's theory.
Online
2010; 1992
114.

Biotechnology [electronic resource]

This program describes three practical applications of DNA technology: the use of gene transfer to improve plant species, the use of molecular probes to quickly identify disease-causing organisms, and the development of antigen vaccines. The program makes very effective use of live video action, animation, and narration to explain and summarize these practical applications in the fast-moving field of genetic engineering.
Online
2005; 1991
115.

Evolution [electronic resource]

Since Charles Darwin formulated his theory of natural selection, our view of the world has changed. Although Darwin's theory itself has "evolved," scientists agree that living species slowly but surely diverged from common ancestors. This program begins with a segment on fossils, one of the most convincing proofs of evolution. It then retraces the major steps of evolution as they were uncovered by science. It also presents the major theories of evolution.
Online
2008; 1991
116.

Double Helix [electronic resource]

This fast-paced dramatization starring well-known actor Jeff Goldblum is about the race to solve one of the greatest mysteries of 20th-century science-the structure of DNA. It is the story of the diligent research, creative analysis, and perseverance of James Watson and Francis Crick that led to the discovery. With the help of their colleague, Maurice Wilkins, they also earned the 1962 Nobel Prize. Students of biology and genetics will benefit from the process of problem-solving used to identify the structure of DNA, as well as the clear, concise summary of research evidence.
Online
2005; 1987
117.

All About Us [electronic resource]: Human Genome

Genetically speaking, only half a percent's difference separates any two human beings in the world, less of a difference than that between any two chimpanzees or gorillas. In this program, Robert Krulwich, the engaging science correspondent for ABC News, joins Eric Lander, professor at MIT's Whitehead Institute, to provide a concise look at the results of the Human Genome Project, a fascinating roundup of discoveries that truly puts the human race in perspective. Using outstanding graphics, Krulwich and Lander discuss the genetic record of the race carried by every person and how many of these genes are dormant-or not even inherently human. William Haseltine, CEO of Human Genome Sciences, and Francis Collins, head of the Human Genome Project, are also interviewed.
Online
2008; 2001
118.

Genetic Engineering [electronic resource]

This program offers an overview of genetics and cloning as they occur both in nature and in the laboratory while addressing the ethical and social implications of genetic engineering. Genes, chromosomes, and DNA are identified, and the process of cell fertilization is demonstrated. Identical human twins are presented as an example of naturally occurring clones. The synthesis of human insulin using recombinant DNA technology, the production of alpha-1 antitrypsin using the milk of transgenic sheep, and the reproductive cloning of animals illustrate applications of genetic engineering. And a case study involving spinal muscular atrophy acts as a platform for discussing therapeutic cloning.
Online
2007; 2001
119.

Who Gets to Know? [electronic resource]: Genetics and Privacy

When it comes to genetic testing, how much should a patient be told? If the news is bad, who else should the patient inform? And could-or should-such privileged information be made available to employers, insurance companies, and others? This Fred Friendly Seminar moderated by Harvard Law School's Arthur Miller offers a compelling discourse on the far-reaching ethical, social, legal, and economic implications of genetic testing. Panelists include U.S. Supreme Court Justice Stephen Breyer; Nancy Wexler, president of the Hereditary Disease Foundation; Cynthia McFadden, ABC News senior legal correspondent; Nadine Strossen, president of the ACLU; and Representative Louise McIntosh Slaughter (D-NY), sponsor of the Genetic Non-discrimination in Health Insurance and Employment Act.
Online
2006; 2003
120.

Making Better Babies [electronic resource]: Genetics and Reproduction

How far should people be allowed to go in trying to have better babies? And whose definition of "better" should prevail? This Fred Friendly Seminar moderated by Dateline NBC correspondent John Hockenberry considers the ethical dilemmas facing individuals and society that grow out of prenatal testing and genetic options that may be available in the future - such as cloning. Panelists include Francis Collins, director of the National Human Genome Research Institute; ABC journalist Meredith Vieira; Princeton University's Lee Silver, author of Remaking Eden: How Genetic Engineering and Cloning Will Transform the American Family; Commissioner Paul Miller of the U.S. Equal Employment Opportunity Commission; Adrienne Asch, Henry R. Luce Professor in Biology, Ethics, and the Politics of Huma [...]
Online
2006; 2003