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Patient-Specific Induced Pluripotent Stem Cell Models [electronic resource]: Generation and Characterization

edited by Andras Nagy, Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada, Kursad Turksen, Ottawa Hospital Research Institute, Ottawa, ON, Canada
Format
EBook; Book; Online
Published
New York : Humana Press, [2016]
Language
English
Series
Springer Protocols
Methods in Molecular Biology
Springer Protocols (Series)
Methods in Molecular Biology (Clifton, N.J.)
ISBN
9781493930333, 1493930338, 9781493930340
Summary
This volume captures the rapid developments in the field of induced pluripotent stem (iPS) cells, which have provided novel opportunities and approaches both for better understanding a number of human diseases and for developing new platforms for drug development and screening for such diseases. Specifically, representative protocols on various disease models have been collected from labs around the world. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Patient-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization is an ideal reference for scientists working on furthering iPS research.--
Contents
  • Generation of patient-specific induced pluripotent stem cell from peripheral blood mononuclear cells by Sendai reprogramming vectors / Oscar Quintana-Bustamante and Jose C. Segovia
  • Doxycycline-inducible system for genetic correction of iPSC disease models / Xiuli Sim [and others]
  • Generation and characterization of patient-specific induced pluripotent stem cell for disease modeling / Renuka Sivapatham and Xianmin Zeng
  • Modeling genomic imprinting disorders using induced pluripotent stem cells / Stormy J. Chamberlain [and others]
  • Generation and characterization of induced pluripotent stem cells from patients with mtDNA mutations / Riikka H. H€am€al€ainen and Anu Suomalainen
  • Skin biopsy and patient-specific stem cell lines / Yao Li, Huy V. Nguyen, and Stephen H. Tsang
  • Directed myogenic differentiation of human induced pluripotent stem cells / Emi Shoji, Knut Woltjen, and Hidetoshi Sakurai
  • Using human induced pluripotent stem cells to model skeletal diseases / Emilie Barruet and Edward C. Hsiao
  • Modeling cardiovascular diseases with patient-specific human pluripotent stem cell-derived cardiomyocytes / Paul W. Burridge [and others]
  • Calcium imaging in pluripotent stem cell-derived cardiac myocytes / Anna Walter [and others]
  • Patient-specific induced pluripotent stem cell models : generation and characterization of cardiac cells / Fabian Zanella and Farah Sheikh
  • Differentiation of human pluripotent stem cells to cardiomyocytes under defined conditions / Cathelijne W. van den Berg [and others]
  • Generation of cardiomyocytes from pluripotent stem cells / Hiroko Nakahama and Elisa Di Pasquale
  • Generation and characterization of patient-specific iPSC model for cardiovascular disease / Yee Ki Lee [and others]
  • Transgene-free disease-specific iPSC generation from fibroblasts and peripheral blood mononuclear cells / Kerem Fidan [and others]
  • Generation and neuronal Differentiation of patient-specific induced pluripotent stem cells derived from Niemann-Pick type C1 fibroblasts / Michaela Trilck, Rayk Hubner, and Moritz J. Frech
  • Multisystemic disease modeling of liver-derived protein folding disorders using induced pluripotent stem cells (iPSCs) / Amy Leung and George J. Murphy
  • In vitro modeling of alcohol-induced liver injury using human-induced pluripotent stem cells / Lipeng Tian, Neha Prasad, and Yoon-Young Jang
  • Generation of human induced pluripotent stem cells using RNA-based sendai virus system and pluripotency validation of the resulting cell population / Valeria Chichagova [and others]
  • Modeling axonal phenotypes with human pluripotent stem cells / Kyle R. Denton, Chong-Chong Xu, and Xue-Jun Li
  • Mitochondrial disease-specific induced pluripotent stem cell models : generation and characterization / Xuan Zhang [and others]
  • Patient-specific induced pluripotent stem cell models : characterization of iPS cell-derived cardiomyocytes / Toru Egashira [and others]
  • Generation of integration-free patient specific iPS cells using episomal plasmids under feeder free conditions / Sara Caxaria [and others].
Description
Mode of access: World wide Web.
Notes
Includes bibliographical references and index.
Series Statement
Springer protocols, 1949-2448
Methods in molecular biology, 1064-3745 ; volume 1353
Springer protocols (Series) 1949-2448
Methods in molecular biology (Clifton, N.J.) ; v. 1353. 1064-3745
Copyright Not EvaluatedCopyright Not Evaluated
Technical Details
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    t| Generation of patient-specific induced pluripotent stem cell from peripheral blood mononuclear cells by Sendai reprogramming vectors / r| Oscar Quintana-Bustamante and Jose C. Segovia -- t| Doxycycline-inducible system for genetic correction of iPSC disease models / r| Xiuli Sim [and others] -- t| Generation and characterization of patient-specific induced pluripotent stem cell for disease modeling / r| Renuka Sivapatham and Xianmin Zeng -- t| Modeling genomic imprinting disorders using induced pluripotent stem cells / r| Stormy J. Chamberlain [and others] -- t| Generation and characterization of induced pluripotent stem cells from patients with mtDNA mutations / r| Riikka H. H€am€al€ainen and Anu Suomalainen -- t| Skin biopsy and patient-specific stem cell lines / r| Yao Li, Huy V. Nguyen, and Stephen H. Tsang -- t| Directed myogenic differentiation of human induced pluripotent stem cells / r| Emi Shoji, Knut Woltjen, and Hidetoshi Sakurai -- t| Using human induced pluripotent stem cells to model skeletal diseases / r| Emilie Barruet and Edward C. Hsiao -- t| Modeling cardiovascular diseases with patient-specific human pluripotent stem cell-derived cardiomyocytes / r| Paul W. Burridge [and others] -- t| Calcium imaging in pluripotent stem cell-derived cardiac myocytes / r| Anna Walter [and others] -- t| Patient-specific induced pluripotent stem cell models : generation and characterization of cardiac cells / r| Fabian Zanella and Farah Sheikh -- t| Differentiation of human pluripotent stem cells to cardiomyocytes under defined conditions / r| Cathelijne W. van den Berg [and others] -- t| Generation of cardiomyocytes from pluripotent stem cells / r| Hiroko Nakahama and Elisa Di Pasquale -- t| Generation and characterization of patient-specific iPSC model for cardiovascular disease / r| Yee Ki Lee [and others] -- t| Transgene-free disease-specific iPSC generation from fibroblasts and peripheral blood mononuclear cells / r| Kerem Fidan [and others] -- t| Generation and neuronal Differentiation of patient-specific induced pluripotent stem cells derived from Niemann-Pick type C1 fibroblasts / r| Michaela Trilck, Rayk Hubner, and Moritz J. Frech -- t| Multisystemic disease modeling of liver-derived protein folding disorders using induced pluripotent stem cells (iPSCs) / r| Amy Leung and George J. Murphy -- t| In vitro modeling of alcohol-induced liver injury using human-induced pluripotent stem cells / r| Lipeng Tian, Neha Prasad, and Yoon-Young Jang -- t| Generation of human induced pluripotent stem cells using RNA-based sendai virus system and pluripotency validation of the resulting cell population / r| Valeria Chichagova [and others] -- t| Modeling axonal phenotypes with human pluripotent stem cells / r| Kyle R. Denton, Chong-Chong Xu, and Xue-Jun Li -- t| Mitochondrial disease-specific induced pluripotent stem cell models : generation and characterization / r| Xuan Zhang [and others] -- t| Patient-specific induced pluripotent stem cell models : characterization of iPS cell-derived cardiomyocytes / r| Toru Egashira [and others] -- t| Generation of integration-free patient specific iPS cells using episomal plasmids under feeder free conditions / r| Sara Caxaria [and others].
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    a| This volume captures the rapid developments in the field of induced pluripotent stem (iPS) cells, which have provided novel opportunities and approaches both for better understanding a number of human diseases and for developing new platforms for drug development and screening for such diseases. Specifically, representative protocols on various disease models have been collected from labs around the world. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Patient-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization is an ideal reference for scientists working on furthering iPS research.-- c| Source other than Library of Congress.
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