Item Details

Print View

Gene Therapy of Cancer: Translational Approaches From Preclinical Studies to Clinical Implementation

edited by Edmund Lattime, Stanton Gerson
Format
EBook; Book; Online
Published
Amsterdam : Academic Press, 2014.
Edition
Third edition
Language
English
ISBN
9780123946324, 0123946328, 9780123942951, 0123942950
Access Restriction
Electronic access is available for UVA students, faculty, staff, and affiliates only. IP address verification required.
Contents
  • Ex Vivo Gene Therapy: Utilization of Genetic Vectors for the Generation of Genetically Modified Cell Products for Therapy
  • Targeting Tumor Vasculature Using Adeno-Associated Virus Phage Vectors Coding Tumor Necrosis Factor-a
  • Viral Insertion Site Detection and Analysis in Cancer Gene Therapy
  • Targeted Systemic Delivery of Therapeutic siRNA
  • Bacterial Delivery of RNAi Effectors
  • Gene-Directed Enzyme Prodrug Cancer Therapy
  • Electroporation Gene Therapy
  • Toxin-Based Cancer Gene Therapy: Under the Control of Oncofetal H19 Regulatory Sequences
  • Gene Therapy in Radiotherapy of Cancer
  • Advances in Oncolytic Virotherapy for Brain Tumors
  • Oncolytic Adenoviruses in the Treatment of Cancer in Humans
  • Selectively Replicating Oncolytic Adenoviruses Combined with Chemotherapy, Radiotherapy, or Molecular Targeted Therapy for Treatment of Human Cancers
  • Reoviral Therapy for Cancer: Strategies for Improving Antitumor Efficacy Using Radio- and Chemotherapy
  • Selectively Replicating Herpes Simplex Viral Vectors
  • Modified Oncolytic Herpesviruses for Gene Therapy of Cancer
  • The Lister Strain of Vaccinia Virus as an Anticancer Therapeutic Agent
  • Poxvirus-Based Strategies for Combined Vaccine and Tumor Microenvironment Manipulation
  • Genetically Engineered (T Cell Receptor) T Cells for AdoptiveTherapy
  • Genetically Modified Dendritic Cell Vaccines for Solid Tumors
  • Dendritic Cell Vaccination
  • Chemokine Gene-Modified Dendritic Cells for Cancer Therapy
  • The Use of T Cell Costimulation to Enhance the Immunogenicity of Tumors
  • Clinical Application of Plasmid-Based Cancer Vaccines
  • Lentivector Vaccines
  • Therapeutic Efficacy and Systemic Antitumor T Cell Immunity Induced by RheoSwitch-Regulated IL-12 Expression after Intratumoral Injection of Adenovirus Vector or Vector-Transduced Dendritic Cells
  • Clinical Trials Using LV-P₁₄₀K-MGMT for Gliomas
  • RNA Interference Therapeutics for Tumor Therapy: Promising Work in Progress
  • MGMT Stem Cell Selection and Protection: Preclinical Large Animal and Clinical Studies
  • Cytidine Deaminase in Myeloprotective Gene Therapy
  • Genetically Engineered Salmonella typhimurium for Targeted Cancer Therapy
  • Imaging of Oncolytic Virus Gene Expression
  • Lentiviral-Encoded Sodium Iodide Symporter-Mediated Cancer Gene Therapy
  • Bacteriophage: From Bacteria to a Successful Targeted Systemic Gene Delivery for Cancer
  • Issues in Moving Gene Therapy Approaches to Early Clinical Trials
  • The FDA Review Process for Cancer Gene Therapy
  • Ethics in Translational Gene Transfer Research.
Description
1 online resource.
Notes
Includes bibliographical references and index.
Copyright Not EvaluatedCopyright Not Evaluated
Technical Details
  • Access in Virgo Classic
  • Staff View

    LEADER 06632cam a2201009Ki 4500
    001 u6413545
    003 SIRSI
    005 20150520070354.9
    006 m o d
    007 cr cnu---unuuu
    008 130909s2014 ne a ob 001 0 eng d
    019
      
      
    a| 861477955
    020
      
      
    a| 9780123946324 q| (electronic bk.)
    020
      
      
    a| 0123946328 q| (electronic bk.)
    020
      
      
    z| 9780123942951
    020
      
      
    z| 0123942950
    035
      
      
    a| (Sirsi) o857769500
    035
      
      
    a| (OCoLC)857769500 z| (OCoLC)861477955
    049
      
      
    a| VAMM n| [Electronic Book/CK]
    040
      
      
    a| N$T b| eng e| rda e| pn c| N$T d| UIU d| OPELS d| YDXCP d| BUF d| OPELS d| OCLCF d| UIU d| OCLCQ d| OCLCO d| VAM d| VZR
    050
      
    4
    a| RC271.G45 b| G485 2014
    060
    1
    0
    a| QZ 266
    060
    0
    4
    a| QZ 266 b| G326 2014
    072
      
    7
    a| HEA x| 039000 2| bisacsh
    072
      
    7
    a| MED x| 014000 2| bisacsh
    072
      
    7
    a| MED x| 022000 2| bisacsh
    072
      
    7
    a| MED x| 112000 2| bisacsh
    072
      
    7
    a| MED x| 045000 2| bisacsh
    082
    0
    4
    a| 616.994042 2| 23
    245
    0
    0
    a| Gene therapy of cancer : b| translational approaches from preclinical studies to clinical implementation / c| edited by Edmund Lattime, Stanton Gerson.
    250
      
      
    a| Third edition.
    264
      
    1
    a| Amsterdam : b| Academic Press, c| 2014.
    300
      
      
    a| 1 online resource.
    336
      
      
    a| text b| txt 2| rdacontent
    337
      
      
    a| computer b| c 2| rdamedia
    338
      
      
    a| online resource b| cr 2| rdacarrier
    504
      
      
    a| Includes bibliographical references and index.
    505
    0
      
    a| Ex Vivo Gene Therapy: Utilization of Genetic Vectors for the Generation of Genetically Modified Cell Products for Therapy -- Targeting Tumor Vasculature Using Adeno-Associated Virus Phage Vectors Coding Tumor Necrosis Factor-a -- Viral Insertion Site Detection and Analysis in Cancer Gene Therapy -- Targeted Systemic Delivery of Therapeutic siRNA -- Bacterial Delivery of RNAi Effectors -- Gene-Directed Enzyme Prodrug Cancer Therapy -- Electroporation Gene Therapy -- Toxin-Based Cancer Gene Therapy: Under the Control of Oncofetal H19 Regulatory Sequences -- Gene Therapy in Radiotherapy of Cancer -- Advances in Oncolytic Virotherapy for Brain Tumors -- Oncolytic Adenoviruses in the Treatment of Cancer in Humans -- Selectively Replicating Oncolytic Adenoviruses Combined with Chemotherapy, Radiotherapy, or Molecular Targeted Therapy for Treatment of Human Cancers -- Reoviral Therapy for Cancer: Strategies for Improving Antitumor Efficacy Using Radio- and Chemotherapy -- Selectively Replicating Herpes Simplex Viral Vectors -- Modified Oncolytic Herpesviruses for Gene Therapy of Cancer -- The Lister Strain of Vaccinia Virus as an Anticancer Therapeutic Agent -- Poxvirus-Based Strategies for Combined Vaccine and Tumor Microenvironment Manipulation -- Genetically Engineered (T Cell Receptor) T Cells for AdoptiveTherapy -- Genetically Modified Dendritic Cell Vaccines for Solid Tumors -- Dendritic Cell Vaccination -- Chemokine Gene-Modified Dendritic Cells for Cancer Therapy -- The Use of T Cell Costimulation to Enhance the Immunogenicity of Tumors -- Clinical Application of Plasmid-Based Cancer Vaccines -- Lentivector Vaccines -- Therapeutic Efficacy and Systemic Antitumor T Cell Immunity Induced by RheoSwitch-Regulated IL-12 Expression after Intratumoral Injection of Adenovirus Vector or Vector-Transduced Dendritic Cells -- Clinical Trials Using LV-P₁₄₀K-MGMT for Gliomas -- RNA Interference Therapeutics for Tumor Therapy: Promising Work in Progress -- MGMT Stem Cell Selection and Protection: Preclinical Large Animal and Clinical Studies -- Cytidine Deaminase in Myeloprotective Gene Therapy -- Genetically Engineered Salmonella typhimurium for Targeted Cancer Therapy -- Imaging of Oncolytic Virus Gene Expression -- Lentiviral-Encoded Sodium Iodide Symporter-Mediated Cancer Gene Therapy -- Bacteriophage: From Bacteria to a Successful Targeted Systemic Gene Delivery for Cancer -- Issues in Moving Gene Therapy Approaches to Early Clinical Trials -- The FDA Review Process for Cancer Gene Therapy -- Ethics in Translational Gene Transfer Research.
    506
      
      
    a| Electronic access is available for UVA students, faculty, staff, and affiliates only. IP address verification required.
    650
      
    0
    a| Cancer x| Gene therapy v| Laboratory manuals.
    650
      
    0
    a| Cancer x| Immunotherapy.
    650
    1
    2
    a| Neoplasms x| genetics.
    650
    1
    2
    a| Neoplasms x| therapy.
    650
    2
    2
    a| Genetic Therapy x| methods.
    650
    2
    2
    a| Immunotherapy x| methods.
    650
    2
    2
    a| Protein Biosynthesis.
    650
      
    7
    a| HEALTH & FITNESS x| Diseases x| General. 2| bisacsh
    650
      
    7
    a| MEDICAL x| Clinical Medicine. 2| bisacsh
    650
      
    7
    a| MEDICAL x| Diseases. 2| bisacsh
    650
      
    7
    a| MEDICAL x| Evidence-Based Medicine. 2| bisacsh
    650
      
    7
    a| MEDICAL x| Internal Medicine. 2| bisacsh
    650
      
    7
    a| Cancer x| Gene therapy. 2| fast 0| (OCoLC)fst00845367
    650
      
    7
    a| Cancer x| Immunotherapy. 2| fast 0| (OCoLC)fst00845386
    655
      
    0
    a| Electronic books.
    655
      
    7
    a| Handbooks, manuals, etc. 2| fast 0| (OCoLC)fst01423877
    700
    1
      
    a| Lattime, Edmund C., d| 1951- e| editor.
    700
    1
      
    a| Gerson, Stanton L., e| editor.
    776
    0
    8
    i| Print version: t| Gene therapy of cancer. b| Third edition z| 9780123942951 w| (OCoLC)839312810
    856
    4
    0
    u| http://proxy01.its.virginia.edu/login?url=https://www.clinicalkey.com/dura/browse/bookChapter/3-s2.0-C2011006951X
    994
      
      
    a| 92 b| VAM
    596
      
      
    a| 19
    999
      
      
    a| RC271.G45 G485 2014 ELECTRONIC w| HS-LC i| 6413545-1001 l| INTERNET m| HEALTHSCI t| E-BOOK
▾See more
▴See less

Availability

Google Preview

Google Books Preview

Read Online