Item Details

Print View

Technological Challenges in Antibiotic Discovery and Development [electronic resource]: A Workshop Summary

Douglas Friedman and Joe Alper, rapporteurs ; Chemical Sciences Roundtable, Board on Chemical Sciences and Technology, Division on Earth and Life Studies, National Research Council of the National Academies
Format
EBook; Book; Online
Published
Washington, D.C. : National Academies Press, [2014]
Language
English
ISBN
9780309298148, 0309298148
Summary
"Technological Challenges in Antibiotic Discovery and Development is the summary of a workshop convened by the Chemical Sciences Roundtable in September 2013 to explore the current state of antibiotic discovery and examine the technology available to facilitate development. Through formal presentations and panel discussions, participants from academia, industry, federal research agencies discussed the technical challenges present and the incentives and disincentives industry faces in antibiotic development, and identified novel approaches to antibiotic discovery. Antibiotic resistance is a serious and growing problem in modern medicine and it is emerging as a pre-eminent public health threat. Each year in the United States alone, at least two million acquire serious infections with bacteria that are resistant to one or more antibiotics, and at least 23,000 people die annually as a direct result of these antibiotic-resistant infections. In addition to the toll on human life, antibiotic-resistant infections add considerable and avoidable costs to the already overburdened U.S. health care system. This report explores the challenges in overcoming antibiotic resistance, screening for new antibiotics, and delivering them to the sites of infection in the body. The report also discusses a path forward to develop the next generation of potent antimicrobial compounds capable of once again tilting the battle against microbial pathogens in favor of humans. Technological Challenges in Antibiotic Discovery and Development gives a broad view of the landscape of antibiotic development and the technological challenges and barriers to be overcome."--Publisher's description
Contents
  • Challenges in overcoming antibiotic resistance
  • Challenges in screening
  • Challenges in drug delivery
  • General observations.
Description
Mode of access: World wide Web.
Notes
Includes bibliographical references.
Copyright Not EvaluatedCopyright Not Evaluated
Technical Details
  • Access in Virgo Classic
  • Staff View

    LEADER 03852cam a22004697i 4500
    001 u6356291
    003 SIRSI
    005 20160408131844.0
    006 m d
    007 cr n
    008 150401s2014 dcua sb 100 0 eng d
    010
      
      
    a| 2015301353
    016
    7
      
    a| 101633065 2| DNLM
    020
      
      
    a| 9780309298148
    020
      
      
    a| 0309298148
    035
      
      
    a| (WaSeSS)ssj0001220615
    040
      
      
    a| NLM b| eng c| NLM d| BTCTA d| AZS d| NRZ d| YDXCP d| OCLCO d| OCLCF d| CDX d| CUT d| DLC d| WaSeSS
    042
      
      
    a| nlmcopyc a| lccopycat
    050
    0
    0
    a| QR177 b| .F75 2014
    082
    0
    4
    a| 615.3/29 2| 23
    100
    1
      
    a| Friedman, Douglas C.
    245
    1
    0
    a| Technological challenges in antibiotic discovery and development h| [electronic resource] : b| a workshop summary / c| Douglas Friedman and Joe Alper, rapporteurs ; Chemical Sciences Roundtable, Board on Chemical Sciences and Technology, Division on Earth and Life Studies, National Research Council of the National Academies.
    260
      
      
    a| Washington, D.C. : b| National Academies Press, c| [2014]
    504
      
      
    a| Includes bibliographical references.
    505
    0
      
    a| Challenges in overcoming antibiotic resistance -- Challenges in screening -- Challenges in drug delivery -- General observations.
    520
      
      
    a| "Technological Challenges in Antibiotic Discovery and Development is the summary of a workshop convened by the Chemical Sciences Roundtable in September 2013 to explore the current state of antibiotic discovery and examine the technology available to facilitate development. Through formal presentations and panel discussions, participants from academia, industry, federal research agencies discussed the technical challenges present and the incentives and disincentives industry faces in antibiotic development, and identified novel approaches to antibiotic discovery. Antibiotic resistance is a serious and growing problem in modern medicine and it is emerging as a pre-eminent public health threat. Each year in the United States alone, at least two million acquire serious infections with bacteria that are resistant to one or more antibiotics, and at least 23,000 people die annually as a direct result of these antibiotic-resistant infections. In addition to the toll on human life, antibiotic-resistant infections add considerable and avoidable costs to the already overburdened U.S. health care system. This report explores the challenges in overcoming antibiotic resistance, screening for new antibiotics, and delivering them to the sites of infection in the body. The report also discusses a path forward to develop the next generation of potent antimicrobial compounds capable of once again tilting the battle against microbial pathogens in favor of humans. Technological Challenges in Antibiotic Discovery and Development gives a broad view of the landscape of antibiotic development and the technological challenges and barriers to be overcome."--Publisher's description
    538
      
      
    a| Mode of access: World wide Web.
    650
      
    0
    a| Drug resistance in microorganisms v| Congresses.
    650
      
    0
    a| Antibiotics x| Research v| Congresses.
    650
      
    0
    a| Public health v| Congresses.
    650
    1
    2
    a| Anti-Bacterial Agents x| therapeutic use v| Congresses.
    650
    1
    2
    a| Drug Resistance, Bacterial v| Congresses.
    650
    2
    2
    a| Bacterial Infections x| drug therapy v| Congresses.
    650
    2
    2
    a| Drug Discovery v| Congresses.
    655
      
    0
    a| Electronic books.
    700
    1
      
    a| Alper, Joe.
    710
    2
      
    a| National Research Council (U.S.). b| Chemical Sciences Roundtable.
    710
    2
      
    a| National Academies Press Free eBooks
    711
    2
      
    a| Technological Challenges in Antibiotic Discovery and Development (Workshop) d| (2013 : c| Washington, D.C.)
    856
    4
    0
    u| http://RE5QY4SB7X.search.serialssolutions.com/?V=1.0&L=RE5QY4SB7X&S=JCs&C=TC0001220615&T=marc
    596
      
      
    a| 1
    999
      
      
    a| XX(6356291.1) w| WEB i| 6356291-1001 l| INTERNET m| UVA-LIB t| INTERNET
▾See more
▴See less

Availability

Google Preview

Google Books Preview

Read Online