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Microfluidics and Nanotechnology [electronic resource]: Biosensing to the Single Molecule Limit

edited by Eric Lagally, Western Governers University, Krzysztof Iniewski, CMOS Emerging Technologies Research Inc., Vancouver, British Columbia, Canada
Format
EBook; Book; Online
Published
Boca Raton : CRC Press, Taylor & Francis Group, [2014]
Language
English
Series
Devices, Circuits, and Systems
ISBN
9781466594906 (hardback : acid-free paper), 146659490X (hardback : acid-free paper)
Summary
"Preface Microtechnology and more recent nanotechnology methods have enabled the fabrication of a wide variety of new chemical and biological sensors. These sensors demonstrate exquisite sensitivity and low limits of detection, enabling exploration of new scientific frontiers. In particular, the novel physics that emerges at small length scales allows parallel, mass-fabricated sensors for detection to both single-cell and single-molecule limits. Stochastic differences between individual cells and molecules have been shown to play important roles in larger biological systems, and these novel sensors have begun to test and elucidate these effects. This book focuses on the combination of soft materials like elastomers and other polymers with materials like semiconductors, metals, and glass to form integrated detection systems for biological and chemical targets. Microfluidic advances in this arena include systems for forming and analyzing tiny droplets (so-called droplet microfluidics); the combination of electrostatic and dielectrics to manipulate droplets on the microscale; miniaturized separation systems, including electrophoresis, for detecting a wide range of genetic targets from single cells; and novel optical and mechanical detection methods at the single-cell and single-molecule scales. This book represents a snapshot of the state of the art from the world's leading microfluidics and nanotechnology laboratories. The combination of different materials at both of these length scales is driving a powerful new set of scientific inquiries that have to date been impossible to address using other technologies. The book is arranged in two major sections. In Part I, the authors discuss a number of unique detection technologies"--
Description
Mode of access: World wide Web.
Notes
Includes bibliographical references and index.
Copyright Not EvaluatedCopyright Not Evaluated
Technical Details
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