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Epigenetic Alterations in Oncogenesis [electronic resource]

Adam R. Karpf, editor
EBook; Book; Online
New York : Springer, c2013.
Advances in experimental medicine and biology
9781441999665 (alk. paper), 1441999663 (alk. paper), 9781441999672 (e-Book), 1441999671 (e-Book)
  • Epigenetic marks and mechanisms
  • DNA methyltransferases, DNA damage repair, and cancer
  • DNA hypomethylation and hemimethylation in cancer
  • Ten eleven translocation enzymes and 5-hydroxymethylation in mammalian development and cancer
  • Altered histone modifications in cancer
  • Nucleosome occupancy and gene regulation during tumorigenesis
  • Impact of epigenetic alterations on cancer biology
  • Epigenetic regulation of miRNAs in cancer
  • DNA hypomethylation and activation of germlike-specific genes in cancer
  • APC and DNA demethylation in cell fate specification and intestinal cancer
  • Epigenetic changes during cell transformation
  • Epigenetic reprogramming of mesenchymal stem cells
  • Clinical implications and analysis in methods
  • Environmental toxicants, epigenetics, and cancer
  • Blood-derived DNA methylation markers of cancer risk
  • Epigenetic therapies in MDS and AML
  • Epigenetic targeting therapies to overcome chemotherapy resistance
  • Methods for cancer epigenome analysis.
Mode of access: World wide Web.
Includes bibliographical references and index.
Series Statement
Advances in experimental medicine and biology, 0065-2598 ; v.754
Advances in experimental medicine and biology v.754. 0065-2598
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