Item Details

The Development of Iron Chelators for Clinical Use

edited by Raymond J. Bergeron, Gary M. Brittenham
Format
Book
Published
Boca Raton : CRC Press, c1994.
Language
English
ISBN
0849386799 (acid-free paper)
Contents
  • Physiology and pathophysiology of iron metabolism: implications for iron chelation therapy in iron overload / P. Ponka
  • Iron, oxidative damage and chelating agents / B. Halliwell
  • Iron chelation therapy in the treatment of iron overload / M.J. Pippard
  • Potential clinical applications of iron chelating therapy / C. Hershko ... [et al.]
  • Iron withholding: the natural defense system and its modification by pharmacologic agents / E.D. Weinberg
  • Iron chelation as a chemotherapeutic strategy in the treatment of malaria / V.R. Gordeuk, G.M. Brittenham, P.E. Thuma
  • Toward better chelation therapy: current concepts and research strategy / H.P. Schnebli ... [et al.]
  • Siderophores as biological deferration agents and the regulation of their synthesis by iron / J.B. Neilands
  • Biochemical and genetic studies on lysine: N-hydroxylase involved in aerobactin synthesis / A.M. Thariath, M.A. Valvano, T. Viswanatha.
  • (cont) Ferrichrome biosynthetic pathway of Ustilago maydis reveals similarities to the aerobactin pathway of Escherichia coli and to globin gene regulation in erythroid cells / S.A. Leong ... [et al.]
  • Ability of catecholate derivatives to promote growth of gram-negative bacteria / R. Reissbrodt, W. Rabsch
  • Synthesis and biological activity of hydroxamate-based iron chelators / R.J. Bergeron, J.S. McManis
  • Siderophore-mediated drug delivery: the design, synthesis and study of siderophore-antibiotic and antifungal conjugates / M.J. Miller, F. Malouin
  • Siderophore-based hydroxpyridonate sequestering agents / K.N. Raymond, J. Xu
  • Ligand design of chelating agents effective in the coordination of Fe(II) and for the removal of iron in cases of iron overload / A.E. Martell ... [et al.]
  • Design of therapeutically useful iron chelators / R.C. Hider, J.B. Porter, S. Singh
  • Comparative evaluation of iron chelators in a primate model / H.H. Peter ... [et al.]
  • Preliminary results from a phase I clinical trial of HBED / R.W. Grady ... [et al.].
Description
xiii, 416 p. : ill. ; 25 cm.
Notes
Includes bibliographical references and index.
Publisher no.
75918
Technical Details
  • Access in Virgo Classic

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    a| Physiology and pathophysiology of iron metabolism: implications for iron chelation therapy in iron overload / P. Ponka -- Iron, oxidative damage and chelating agents / B. Halliwell -- Iron chelation therapy in the treatment of iron overload / M.J. Pippard -- Potential clinical applications of iron chelating therapy / C. Hershko ... [et al.] -- Iron withholding: the natural defense system and its modification by pharmacologic agents / E.D. Weinberg -- Iron chelation as a chemotherapeutic strategy in the treatment of malaria / V.R. Gordeuk, G.M. Brittenham, P.E. Thuma -- Toward better chelation therapy: current concepts and research strategy / H.P. Schnebli ... [et al.] -- Siderophores as biological deferration agents and the regulation of their synthesis by iron / J.B. Neilands -- Biochemical and genetic studies on lysine: N-hydroxylase involved in aerobactin synthesis / A.M. Thariath, M.A. Valvano, T. Viswanatha.
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    0
      
    a| (cont) Ferrichrome biosynthetic pathway of Ustilago maydis reveals similarities to the aerobactin pathway of Escherichia coli and to globin gene regulation in erythroid cells / S.A. Leong ... [et al.] -- Ability of catecholate derivatives to promote growth of gram-negative bacteria / R. Reissbrodt, W. Rabsch -- Synthesis and biological activity of hydroxamate-based iron chelators / R.J. Bergeron, J.S. McManis -- Siderophore-mediated drug delivery: the design, synthesis and study of siderophore-antibiotic and antifungal conjugates / M.J. Miller, F. Malouin -- Siderophore-based hydroxpyridonate sequestering agents / K.N. Raymond, J. Xu -- Ligand design of chelating agents effective in the coordination of Fe(II) and for the removal of iron in cases of iron overload / A.E. Martell ... [et al.] -- Design of therapeutically useful iron chelators / R.C. Hider, J.B. Porter, S. Singh -- Comparative evaluation of iron chelators in a primate model / H.H. Peter ... [et al.] -- Preliminary results from a phase I clinical trial of HBED / R.W. Grady ... [et al.].
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    a| Iron Chelating Agents x| therapeutic use.
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    a| Brittenham, Gary M.
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