Item Details

Applied Biopharmaceutics and Pharmacokinetics

Leon Shargel, Andrew B.C. Yu
Format
Book
Published
Norwalk, Conn. : Appleton & Lange, c1993.
Edition
3rd ed
Language
Undetermined
ISBN
083850129X
Contents
  • Review of mathematical fundamentals
  • Rates and orders of reactions
  • Introduction to pharmacokinetics
  • One-compartment open model
  • Multicompartment models
  • Drug distribution and protein binding
  • Physiologic factors related to drug absorption
  • Biopharmaceutic consideration in drug product design
  • Pharmacokinetics of drug absorption
  • Bioavailability and bioequivalence
  • Modified-release drug products and targeted drug delivery systems
  • Drug clearance
  • Hepatic elimination of drugs
  • Intravenous infusion
  • Multiple-dosage regimens
  • Nonlinear pharmacokinetics
  • Application of pharmacokinetics in clinical situations
  • Dosage adjustment in renal disease
  • Relationship between pharmacokinetics and pharmacologic response
  • Physiologic pharmacokinetic models, statistical moment, and mean residence time.
Description
xxii, 625 p. : ill. ; 26 cm.
Notes
Includes bibliographical references and index.
Publisher no.
71259
Technical Details
  • Access in Virgo Classic

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    a| Review of mathematical fundamentals -- Rates and orders of reactions -- Introduction to pharmacokinetics -- One-compartment open model -- Multicompartment models -- Drug distribution and protein binding -- Physiologic factors related to drug absorption -- Biopharmaceutic consideration in drug product design -- Pharmacokinetics of drug absorption -- Bioavailability and bioequivalence -- Modified-release drug products and targeted drug delivery systems -- Drug clearance -- Hepatic elimination of drugs -- Intravenous infusion -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Application of pharmacokinetics in clinical situations -- Dosage adjustment in renal disease -- Relationship between pharmacokinetics and pharmacologic response -- Physiologic pharmacokinetic models, statistical moment, and mean residence time.
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