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Maternal Lifestyle Study in Four Sites in the United States, 1993-2011 [electronic resource]

Barry Lester, Henrietta Bada, Charles Bauer, Seetha Shankaran, Toni Whitaker, Linda LaGasse, Jane Hammond
Format
Computer Resource; Online
Published
Ann Arbor, Mich. Inter-university Consortium for Political and Social Research [distributor] 2014
Edition
2016-03-31
Series
ICPSR
ICPSR (Series)
Access Restriction
AVAILABLE. This study is freely available to the general public.
Abstract

The Maternal Lifestyle Study (MLS) was the largest of the NIH longitudinal studies of children with prenatal cocaine exposure (PCE). MLS was a longitudinal multi-site observational study of the long-term effects of in-utero exposure to cocaine on child development. MLS was conducted at four geographically diverse, collaborating university centers (Wayne State University, University of Tennessee at Memphis, University of Miami, and Brown University). Participants were identified during the newborn period while in the hospital. The MLS began enrollment of a longitudinal birth cohort of 1,388 infant/mother dyads in 1993. Subjects in the follow-up were seen from 1 month of age through 16 years of age. The overall purpose of the study was to investigate the effects of drug use during pregnancy on acute neonatal events and long-term physical health, social, behavioral and neurodevelopmental outcomes.

The study included five phases of data collection. The first phase examined acute effects of maternal substance use on infant health outcomes at birth. The four subsequent follow-up phases examined development across the following periods: Phase II -- 1-36 months; Phase III -- 4-7 years; Phase IV -- 8-11 years; Phase V -- 12-16 years. In Phase I, the study screened 19,079 infants between May 1993 and May 1995. Mothers at these centers were enrolled in the study within 24 hours after delivery. Initial screening included the mother's labor and delivery chart, the newborn admission chart, and a meconium sample. Infant meconium was collected and samples were express shipped to a central laboratory for analysis of metabolites of illicit drugs. Additionally, a drug use questionnaire that addressed the mother's use during pregnancy of nicotine, alcohol, marijuana, cocaine, opiates, and other illicit drugs was given by research staff that were trained and certified in the reliable administration of all of the study interviews. A mother-child dyad was considered exposed if a mother admitted to using cocaine during pregnancy and/or there was a positive meconium assay for cocaine metabolites including gas chromatography/mass spectrometry confirmation. Nonexposed children were those who were born to mothers who denied cocaine use, confirmed by negative meconium test results. Acute outcomes evaluated in Phase I included: central nervous system (CNS) and autonomic nervous system (ANS) findings and symptoms, abruption placenta, fetal growth retardation, congenital malformations, respiratory distress syndrome, chronic lung disease, intraventricular hemorrhage, necrotizing enterocolitis, retinopathy of prematurity, and periventricular leukomalacia.

From the initial Phase I cohort of 8,627 dyads, 1,388 participants for the longitudinal follow-up were recruited at a 1-month visit. The sample included a cohort of exposed infants (n = 658) who were group matched within site with a group of non-exposed comparison infants (n=730) by gestational age categories (32, 33-36, and 36 weeks) and child gender, race, and ethnicity. At the 1-month visit, the biological mother was interviewed for a detailed inventory of her legal and illegal drug use during pregnancy using the Maternal Interview of Substance Use (MISU). Phase II examined the first 36 months of life for the sample of 1,388. Follow-up visits occurred at 1, 4, 7, 9, 12, 18, 24, and 36 months (corrected age). Outcomes examined included physical health, developmental, behavioral, social, and environmental outcomes. Phase III followed children at 4, 4.5, 5, 6, and 7 years. In addition to outcomes examined in Phase II, school performance and neurodevelopmental measures of emotional and behavioral self-regulation were also examined. Phase IV covers ages 8, 9, 10, and 11 years of age. Outcomes in this phase were further expanded to include antisocial behavior, onset of substance use, psychopathology, and neuroendocrine function. Phase V assessed children at ages 12, 13, 14, 15, and 16 years of age. The fifth phase of the study has a significant emphasis on psychopathology, school performance, peer relationships, substance use onset and risk taking behaviors, including risky sexual behaviors.

Contents
  • Prenatal Cocaine and Opiate Exposure Data
  • Body Mass Index Data, Birth to Year 16
  • Phase I: Subject Matching Data
  • Phase I: Recruitment Data
  • Phase I: Participant Data
  • Phase II: Demographic and Drug Screen Data
  • Phase II: M01 Administrative Data
  • Phase II: M01 Mother/Caregiver Report Data
  • Phase II: M01 Mother/Caregiver Report Data, Addiction Severity Index
  • Phase II: M01 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
  • Phase II: M01 Child Performance Data
  • Phase II: M01 Medical Data, 1 Month Interval Medical History
  • Phase II: M01 Medical Data, Cranial Ultrasound
  • Phase II: M01 Supplement Data, Cry Analysis
  • Phase II: M04 Administrative Data
  • Phase II: M04 Mother/Caregiver Report Data
  • Phase II: M04 Mother/Caregiver Report Data, Agency Report
  • Phase II: M04 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
  • Phase II: M04 Child Performance Data
  • Phase II: M04 Examiner Evaluation Data, Checklist for Comfort Strategies
  • Phase II: M04 Examiner Evaluation Data, BAIT Scores
  • Phase II: M04 Medical Data, Interval Medical History
  • Phase II: M04 Child Performance Data, BAIT Physiology
  • Phase II: M04 Child Performance Data, Face-to-Face Still-Face Paradigm
  • Phase II: M08 Administrative Data
  • Phase II: M08 Mother/Caregiver Report Data
  • Phase II: M08 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
  • Phase II: M08 Medical Data, Interval Medical History
  • Phase II: M08 Medical Data, Neurological Examination
  • Phase II: M10 Administrative Data
  • Phase II: M10 Mother/Caregiver Report Data
  • Phase II: M10 Examiner Evaluation Data
  • Phase II: M12 Administrative Data
  • Phase II: M12 Mother/Caregiver Report Data
  • Phase II: M12 Mother/Caregiver Report Data, Agency Report
  • Phase II: M12 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
  • Phase II: M12 Child Performance Data
  • Phase II: M12 Examiner Evaluation Data
  • Phase II: M12 Medical Data, Interval Medical History
  • Phase II: M12 Medical Data, Neurological Examination
  • Phase II: M12 Child Performance Data, Mastery Motivation
  • Phase II: M18 Administrative Data
  • Phase II: M18 Mother/Caregiver Report Data
  • Phase II: M18 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
  • Phase II: M18 Child Performance Data
  • Phase II: M18 Examiner Evaluation Data, Checklist for Comfort Strategies
  • Phase II: M18 Examiner Evaluation Data, Attachment - Strange Situation
  • Phase II: M18 Child Performance Data, Mastery Motivation
  • Phase II: M24 Administrative Data
  • Phase II: M24 Mother/Caregiver Report Data
  • Phase II: M24 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
  • Phase II: M24 Child Performance Data
  • Phase II: M24 Medical Data
  • Phase II: M24 Child Performance Data, Mastery Motivation
  • Phase II: M30 Administrative Data
  • Phase II: M30 Mother/Caregiver Report Data
  • Phase II: M30 Mother/Caregiver Report Data, Peabody Picture Vocabulary Test
  • Phase II: M30 Child Performance Data
  • Phase II: M30 Examiner Evaluation Data
  • Phase II: M36 Administrative Data
  • Phase II: M36 Mother/Caregiver Report Data
  • Phase II: M36 Mother/Caregiver Report Data, CPS and Foster Care, Long Form
  • Phase II: M36 Mother/Caregiver Report Data, Lead Exposure Risk Assessment
  • Phase II: M36 Mother/Caregiver Report Data, Peabody Picture Vocabulary Test
  • Phase II: M36 Child Performance Data
  • Phase II: M36 Examiner Evaluation Data, Psychological Impairment Rating Scale, Adult
  • Phase II: M36 Examiner Evaluation Data, Psychological Impairment Rating Scale, Child
  • Phase II: M36 Examiner Evaluation Data, Attachment - Strange Situation
  • Phase II: M36 Examiner Evaluation Data, Census Characteristics
  • Phase II: M36 Examiner Evaluation Data, Checklist for Comfort Strategies
  • Phase II: M36 Medical Data
  • Phase II: M36 Child Performance Data, Mastery Motivation
  • Phase III: Y4 Administrative Data
  • Phase III: Y4 Mother/Caregiver Report Data
  • Phase III: Y4 Mother/Caregiver Report Data, Addiction Severity Index (ASI)
  • Phase III: Y4 Mother/Caregiver Report Data, Addiction Severity Index (ASI), Scoring
  • Phase III: Y4 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
  • Phase III: Y4 Child Performance Data
  • Phase III: Y4 Child Performance Data Supplemental
  • Phase III: Y4 Examiner Evaluation Data, Checklist for Comfort Strategies
  • Phase III: Y4 Examiner Evaluation Data, Psychological Impairment Rating Scale, Adult
  • Phase III: Y4 Examiner Evaluation Data, Psychological Impairment Rating Scale, Child
  • Phase III: Y4 Medical Data
  • Phase III: Y4.5 Medical Data Administrative Data
  • Phase III: Y4.5 Mother/Caregiver Report Data
  • Phase III: Y4.5 Mother/Caregiver Report Data, Child Abuse Potential (CAP) Inventory
  • Phase III: Y4.5 Child Performance Data
  • Phase III: Y4.5 Examiner Evaluation Data
  • Phase III: Y4.5 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Adult
  • Phase III: Y4.5 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Child
  • Phase III: Y5 Administrative Data
  • Phase III: Y5 Mother/Caregiver Report Data
  • Phase III: Y5 Mother/Caregiver Report Data, Child Protective Services and Foster Care - Long
  • Phase III: Y5 Mother/Caregiver Report Data, Caretaker Inventory of Substance Use (CISU) - Abuse
  • Phase III: Y5 Mother/Caregiver Report Data, Peabody Picture Vocabulary Test
  • Phase III: Y5 Mother/Caregiver Report Data, Peabody Picture Vocabulary Test, Scoring
  • Phase III: Y5 Child Performance Data
  • Phase III: Y5 Child Performance Data Supplemental
  • Phase III: Y5 Examiner Evaluation Data
  • Phase III: Y5 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Adult
  • Phase III: Y5 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Child
  • Phase III: Y5 Medical Data
  • Phase III: Y5.5 Administrative Data
  • Phase III: Y5.5 Mother/Caregiver Report Data
  • Phase III: Y5.5 Examiner Evaluation Data
  • Phase III Y6 Administrative Data
  • Phase III Y6 Mother/Caregiver Report Data
  • Phase III Y6 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
  • Phase III Y6 Mother/Caregiver Report; Caretaker Inventory of Substance Use (CISU) - Abuse
  • Phase III Y6 Child Performance Data
  • Phase III Y6 Child Performance Data, Supplement
  • Phase III Y6 Examiner Evaluation Data, Empathy
  • Phase III Y6 Examiner Evaluation Data, Comfort Strategies
  • Phase III Y6 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Adult
  • Phase III Y6 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Child
  • Phase III Y6 Medical Data
  • Phase III Y7 Administrative Data
  • Phase III Y7 Mother/Caregiver Report Data
  • Phase III Y7 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
  • Phase III Y7 Mother/Caregiver Report; Caretaker Inventory of Substance Use (CISU) - Abuse
  • Phase III Y7 Child Performance Data
  • Phase III Y7 Child Report Data
  • Phase III Y7 Teacher Report Data
  • Phase III Y7 Examiner Evaluation Data
  • Phase III Y7 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Child
  • Phase III Y7 Medical Data
  • Phase IV Y8 Administrative Data
  • Phase IV Y8 Mother/Caregiver Report Data
  • Phase IV Y8 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
  • Phase IV Y8 Mother/Caregiver Report; Caretaker Inventory of Substance Use (CISU) - Abuse
  • Phase IV Y8 Child Performance Data
  • Phase IV Y8 Child Report Data
  • Phase IV Y8 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Adult
  • Phase IV Y8 Examiner Evaluation Data, Psychological Impairment Rating Scale (PIRS) - Child
  • Phase IV Y8 Medical Data
  • Phase IV Y9 Administrative Data
  • Phase IV Y9 Mother/Caregiver Report Data
  • Phase IV Y9 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
  • Phase IV Y9 Child Performance Data, Cambridge Neuropsychological Test Automated Battery
  • Phase IV Y9 Child Performance Data
  • Phase IV Y9 Child Report Data
  • Phase IV Y9 Teacher Report Data
  • Phase IV Y9 Teacher Report Data Mock Report Card
  • Phase IV Y9 Examiner Evaluation Data
  • Phase IV Y9 Medical Data
  • Phase IV Y10 Administrative Data
  • Phase IV Y10 Mother/Caregiver Report Data
  • Phase IV Y10 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
  • Phase IV Y10 Mother/Caregiver Report, Caretaker Inventory of Substance Use (CISU) - Abuse and Coping With Children's Negative Emotion Scale (CCNES)
  • Phase IV Y10 Child Performance Data
  • Phase IV Y10 Child Report Data
  • Phase IV Y10 Child Report Data, Affect Elicitation
  • Phase IV Y10 Medical Data
  • Phase IV Y11 Administrative Data
  • Phase IV Y11 Mother/Caregiver Report Data
  • Phase IV Y11 Mother/Caregiver Report Data, Lifestyle Inventory of Family History (LIFH) -R
  • Phase IV Y11 Mother/Caregiver Report Data, Lifestyle Inventory of Family History (LIFH) -B
  • Phase IV Y11 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
  • Phase IV Y11 Mother/Caregiver Report Data, Addiction Severity Index (ASI)
  • Phase IV Y11 Child Performance Data
  • Phase IV Y11 Child Report Data
  • Phase IV Y11 Child Report Data, Children's Eating Attitude Test (ChEAT)
  • Phase IV Y11 Teacher Report Data
  • Phase IV Y11 Examiner Evaluation
  • Phase IV Y11 Medical Data
  • Phase V Y12 Administrative Data
  • Phase V Y12 Mother/Caregiver Report Data
  • Phase V Y12 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
  • Phase V Y12 Child Performance Data
  • Phase V Y12 Child Report Data
  • Phase V Y12 Medical Data
  • Phase V Y13 Administrative Data
  • Phase V Y13 Mother/Caregiver Report Data
  • Phase V Y13 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
  • Phase V Y13 Mother/Caregiver Report Data, Caretaker Inventory of Substance Use (CISU) - Abuse
  • Phase V Y13 Child Performance Data
  • Phase V Y13 Child Report Data
  • Phase V Y13 Examiner Evaluation
  • Phase V Y13 Medical Data
  • Phase V Y14 Administrative Data
  • Phase V Y14 Mother/Caregiver Report Data
  • Phase V Y14 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
  • Phase V Y14 Mother/Caregiver Report Data, Caretaker Inventory of Substance Use (CISU) - Abuse
  • Phase V Y14 Child Report Data
  • Phase V Y14 Child Report Data, Affect Elicitation
  • Phase V Y14 Child Report Data, Children's Emphatic Attitudes Questionnaire (CEAQ)
  • Phase V Y14 Medical Data
  • Phase V Y15 Administrative Data
  • Phase V Y15 Mother/Caregiver Report Data
  • Phase V Y15 Mother/Caregiver Report Data, Child Protective Services & Foster Care - Long
  • Phase V Y15 Mother/Caregiver Report Data, Antisocial Process Screening Device
  • Phase V Y15 Mother/Caregiver Report Data, Parent Report on Child's Close Friends
  • Phase V Y15 Mother/Caregiver Report Data, Caretaker Inventory of Substance Use (CISU) - Abuse
  • Phase V Y15 Child Performance Data
  • Phase V Y15 Child Performance Data, Balloon Analogue Risk Task-Youth (BART-Y) Main Balloon (summary)
  • Phase V Y15 Child Report Data
  • Phase V Y15 Child Report Data, About My Parent
  • Phase V Y15 Child Report Data, Adolescent Health Behavior Survey (AHBS)
  • Phase V Y15 Medical Data
  • Phase V Y16 Administrative Data
  • Phase V Y16 Mother/Caregiver Report Data
  • Phase V Y16 Child Report Data
  • Phase V Y16 Medical Data
Description
Mode of access: Intranet.
Notes
Title from ICPSR DDI metadata of 2016-04-01.
Series Statement
ICPSR 34312
ICPSR (Series) 34312
Other Forms
Also available as downloadable files.
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